银杏-元宝枫制成的软胶囊对人体记忆改善的研究毕业论文_林学毕业论文

银杏-元宝枫制成的软胶囊对人体记忆改善的研究毕业论文

2021-04-20更新

摘 要

本研究旨在探讨以银杏叶与元宝枫油按照比例为内容物制成的宝枫三益软胶囊在辅助改善记忆的作用。采用自身与组间两种对照设计。纳入120例受试者,随机分为试食组和对照组。试食组按要求服用宝枫三益软胶囊,对照组服用安慰剂,连续服用30天。试验结束有效例数113例,试食组57例,对照组56例;脱失7例,总脱失率为5.8%。试验前两组受试者性别、年龄、文化程度以及各记忆量表分、记忆商组间比较,差异均无统计学意义(P>0.05),表明两组一般资料具有可比性。试食组试验前后各记忆量表分、记忆商组内自身比较,差异均有统计学意义(P<0.05)。试验后试食组各记忆量表分(除图像人像特点联系回忆量表分、自由回忆量表分外)、记忆商与对照组比较,差异均有统计学意义(P<0.05)。两组间试验前后各记忆量表分(除图像自由回忆量表分、人像特点联系回忆量表分外)、记忆商的差值比较,差异均有统计学意义(P<0.05)。综合以上结果显示,银杏元宝枫制成的软胶囊对人体记忆功能有改善作用。

关键词:银杏;元宝枫;宝枫三益软胶囊,改善记忆

The Study on the Improvement of the Memory of the Human Body by the Soft Capsule Made of the Ginkgo of Ginkgo

ABSTRACT

The objective of this study is to investigate the effect of Baofeng Sanyi soft capsule made from Ginkgo biloba leaves and Yuanbao Maple oil in improving memory. Two kinds of control designs were designed between themselves and between groups. 120 subjects were randomly divided into trial group and control group. The trial group was required to take Baofeng Sanyi soft capsule, while the control group was given placebo for 30 days. At the end of the experiment, 113 cases were effective, 57 cases in the trial group and 56 cases in the control group, and 7 cases were lost, the total loss rate was 5.8%. There were differences in age, sex, educational level, memory scale score and memory quotient between the two groups before the experiment. There was no significant difference between the two groups (Pgt;0.05). The scores of memory and memory in the test group and the memory quotient group were statistically significant (Plt;0.05). After the test, the memory volume of the test group was divided (except for the image free recall scale, the feature of the portrait and the recall scale), and the difference between the memory and the control group was statistically significant (Plt;0.05). The difference between the two groups was statistically significant (Plt;0.05), except for the image free memory scale score, the portrait characteristic and the recall scale), and the difference of the memory quotient (Plt;0.05) In conclusion, the soft capsule made of Ginkgo biloba maple can improve the memory function of human body.

Key words: ginkgo biloba; Yuanbaofeng; Baofeng Sanyi soft capsule to improve memory

目 录

1 前言 – 1 –

1.1神经酸 – 1 –

1.2宝枫三益软胶囊的药理作用 – 1 –

1.3研究的目的及意义 – 1 –

1.4国内外研究情况 – 2 –

1.5特色与创新 – 3 –

2 材料和方法 – 4 –

2.1样品 – 4 –

2.2受试对象 – 4 –

2.3 试验设计及分组 – 4 –

2.4 食用剂量及方法 – 4 –

2.5 主要仪器 – 4 –

2.6 观察指标 – 4 –

2.6.1安全性指标 – 4 –

2.6.2 功效性观察 – 5 –

2.7 数据统计 – 5 –

2.8结果判定 – 5 –

3 结果 – 6 –

3.1 试验前一般资料均衡性比较 – 6 –

3.2 对人体安全性指标的影响 – 6 –

3.2.1 受试者一般状况 – 6 –

3.2.2 受试者血压、心率检查 – 7 –

3.2.3 血常规检查 – 7 –

3.2.4 肝肾功能及血液生化指标检查 – 8 –

3.2.5 胸透、心电图、腹部B超及尿、粪常规检查 – 9 –

3.2.6 不良反应记录 – 9 –

3.3 对功效性指标影响 – 9 –

3.3.1对指向记忆量表分的影响 – 9 –

3.3.2对联想学习记忆量表分的影响 – 10 –

3.3.3对图像自由回忆量表分的影响 – 10 –

3.3.4对无意义图像再认量表分的影响 – 10 –

3.3.5对人像特点联系回忆量表分的影响 – 11 –

3.3.6对记忆商的影响 – 11 –

结 论 – 12 –

致 谢 – 13 –

参考文献 – 14 –

  1. 前言

1.1神经酸

神经酸是大脑神经组织和神经细胞的天然关键成分。一方面神经酸可以修复受损神经组织,帮助大脑神经组织末梢保持活性,使神经细胞重生。另一方面神经酸对视神经细胞、大脑细胞、周围神经细胞的生长、发育和维持有积极的影响。缺少神经酸,将会引起多种脑疾病(老年痴呆、脑萎缩、失眠健忘、脑中风等)。当摄入神经酸后, 大脑白质得到及时补充, 神经元细胞的生物膜结构得到改善, 提高了细胞活性, 有助于推迟衰老[1]

1.2宝枫三益软胶囊的药理作用

元宝枫籽油中神经酸含量高达5%。神经酸在修复大脑的神经传递通道方面具有很强的作,此外,神经酸对神经末梢恢复活性,促进大脑中神经细胞的生长也具有相当好的疗效[2]

银杏叶提取物中富含的银杏黄酮和银杏内酯类化合物是其主要活性物质[3-4],能够改变大脑内的血液流变学并且扩张大脑血管,促进大脑的微循环,从而可增加大脑的样供应量。有助于改善记忆力。银杏叶提取物中主要的活性成分中黄酮最高可达到24%,还包括白果内酯以及银杏内酯[5]

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